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IGF-IR (phospho Tyr1161) rabbit pAb

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ES1334

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

Product name:	IGF-IR (phospho Tyr1161) rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; Insulin receptor; IR; CD antigen CD220
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1161. AA range:1131-1180
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	pro: 155kD, recetor beta: 95kD
GeneID:	3480/3643
Human Swiss-Prot No:	P08069/P06213
Cellular localization:	Cell membrane ; Single-pass type I membrane protein .
Background:	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

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