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IGF-IR (phospho Tyr1165/Y1166) rabbit pAb
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ES1335
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: IGF-IR (phospho Tyr1165/Y1166) rabbit pAb
Reactivity: Human;Mouse;Rat;Monkey
Alternative Names: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: pro: 155kD, recetor beta: 95kD
GeneID: 3480
Human Swiss-Prot No: P08069
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
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